Mario, a game developer, and his friends must tackle and escape from a rising zombie apocalypse in the region of Rayalaseema. In a televised broadcast, Prime Minister Narendra Modi announces that a lockdown will be implemented to prevent the deadly coronavirus which has spread to India. A man with a knife follows an older man back to his home. Upon reaching the older man’s home, the man is attacked and knocked unconscious. He wakes up on an operating table in a hidden lab. A masked figure injects him with a serum. The serum turns the man into a zombie.
Marripalem Obul Reddy, alias “Mario,” wakes up to a text from his friend Bhadram that the lockdown has finally been lifted. A joyful Mario goes to breakfast with his mother, father, Pratap Reddy, and sister Preeti. Pratap berates his son for being a gamer and tells him to get a real job. Mario corrects his father, telling him that he is a game designer.